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Question: All of the following are true regarding the PML-RARα fusion protein EXCEPT: a. it induces the se…

by | Dec 5, 2023 | Posted Questions

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All of the following are true regarding the PML-RARα fusion
protein EXCEPT:

a. it induces the self-renewal of Acute Promyelociyic Leukemia
(APL) cells

b. it blocks differentiation

c. it can be blocked by high pharmacological levels of retinoic
acid (RA)

d. it can be blocked by physiological levels of retinoic acid
(RA)

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